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The CD40-CD154 axis in transplantation: from immunobiology to therapeutic targeting

The CD40-CD154 costimulatory axis serves as a central hub bridging innate and adaptive immunity, regulating antigen presentation, T-cell priming, B-cell activation, germinal center formation, and antibody class switching. In transplantation, this pathway drives donor-reactive T-cell expansion, dendr...

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Váldodahkkit: Kunxiong Wang, Tao Li, Ting Yan, Hidetaka Hara, Yi Wang
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2026-05-01
Ráidu:Frontiers in Immunology
Fáttát:
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1825653/full
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