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Human Cytomegalovirus Latency and Reactivation in Allogeneic Hematopoietic Stem Cell Transplant Recipients

Human cytomegalovirus (HCMV) reactivation is a major infectious cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). HCMV is a ubiquitous beta-herpesvirus which asymptomatically infects immunocompetent individuals but establishes lifelong latency, with th...

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Main Authors: Lauren Stern, Barbara Withers, Selmir Avdic, David Gottlieb, Allison Abendroth, Emily Blyth, Barry Slobedman
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Microbiology
Subjects:
human cytomegalovirus
HCMV
CMV
latency
reactivation
hematopoietic stem cell transplant
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01186/full
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