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GelMA hydrogel dual photo-crosslinking to dynamically modulate ECM stiffness

The dynamic nature of the extracellular matrix (ECM), particularly its stiffness, plays a pivotal role in cellular behavior, especially after myocardial infarction (MI), where cardiac fibroblasts (cFbs) are key in ECM remodeling. This study explores the effects of dynamic stiffness changes on cFb ac...

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Principais autores: Josephina J. H. M. Smits, Atze van der Pol, Marie José Goumans, Carlijn V. C. Bouten, Ignasi Jorba
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-06-01
coleção:Frontiers in Bioengineering and Biotechnology
Assuntos:
GelMA
mechanical memory
cardiac fibroblast (cFb)
ECM
stiffness
tissue engineeering
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1363525/full
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