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Astrocytes gate Hebbian synaptic plasticity in the striatum

Astrocytes regulate synaptic signalling via EAAT glutamate uptake, though whether they play a role in Hebbian plasticity is unknown. Here, the authors find targeting EAAT2 disrupts the emergence of spike timing-dependent plasticity, which highlights the role of astrocytes as gatekeepers for Hebbian...

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Bibliografiske detaljer
Principais autores: Silvana Valtcheva, Laurent Venance
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2016-12-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/ncomms13845
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