Aspartate decarboxylase (PanD) as a new target of pyrazinamide in Mycobacterium tuberculosis
Pyrazinamide (PZA) is a frontline anti-tuberculosis drug that plays a crucial role in the treatment of both drug-susceptible and multidrug-resistant tuberculosis (MDR-TB). PZA is a prodrug that is converted to its active form, pyrazinoic acid (POA), by a nicotinamidase/pyrazinamidase encoded by the...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis Group
2014-01-01
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| Seria: | Emerging Microbes and Infections |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.tandfonline.com/doi/10.1038/emi.2014.61 |
| Etykiety: |
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