Effects of inhaled bronchodilators on dynamic lung mechanics during exercise in COPD: protocol for a randomised, placebo-controlled crossover trial

Background Activity-related dyspnoea in moderate–severe COPD is centrally related to heightened wasted ventilation in the physiological dead space colliding with constraints to tidal expansion due to acute-on-chronic gas trapping. Both phenomena are ultimately related to small airway dysfunction. Ho...

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Detalhes bibliográficos

Principais autores:	Karam Alosta, Matthew D. James, Sandra G. Vincent, Reginald M. Smyth, Abed A. Hijleh, Guilherme D. Back, Alessandro Porcella, Nicolle J. Domnik, Denis E. O'Donnell, J. Alberto Neder
Formato:	Artigo
Idioma:	Inglês
Publicado em:	European Respiratory Society 2025-11-01
coleção:	ERJ Open Research
Acesso em linha:	https://doi.org/10.1183/23120541.01323-2024
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