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Generation of New Hairless Alleles by Genomic Engineering at the Hairless Locus in Drosophila melanogaster.

Hairless (H) is the major antagonist within the Notch signalling pathway of Drosophila melanogaster. By binding to Suppressor of Hairless [Su(H)] and two co-repressors, H induces silencing of Notch target genes in the absence of Notch signals. We have applied genomic engineering to create several ne...

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主要な著者: Heiko Praxenthaler, Thomas K Smylla, Anja C Nagel, Anette Preiss, Dieter Maier
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2015-01-01
シリーズ:PLoS ONE
オンライン・アクセス:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0140007&type=printable
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