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Dapagliflozin Plus Metformin Versus Metformin Alone in Overweight and Obese Patients with Polycystic Ovary Syndrome - An Open-Label, Parallel, Randomized Controlled Trial

Introduction: Insulin resistance plays the central role in the pathophysiology of polycystic ovary syndrome (PCOS). While metformin is widely used, its metabolic and androgen-lowering benefits are modest and often limited by tolerability, highlighting the need to evaluate newer therapeutic agents ta...

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Hlavní autoři: Vishal Agarwal, Sambit Das, Arun K. Choudhury, Dayanidhi Meher, Devadarshini Sahoo, Sandeep K. Sahu, Subhadra Priyadarshini, Sonam J. Agarwal, Binod Prusty, Bijay K. Das, Amogh S. Chappalagavi, Sheenam Gupta
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer Medknow Publications 2026-01-01
Edice:Indian Journal of Endocrinology and Metabolism
Témata:
dapagliflozin
hyperandrogenism
metformin
polycystic ovary syndrome
sglt-2 inhibitors
On-line přístup:https://journals.lww.com/10.4103/ijem.ijem_635_25
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