sciMET-cap: high-throughput single-cell methylation analysis with a reduced sequencing burden

Abstract DNA methylation is a key component of the mammalian epigenome, playing a regulatory role in development, disease, and other processes. Robust, high-throughput single-cell DNA methylation assays are now possible (sciMET); however, the genome-wide nature of DNA methylation results in a high s...

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Autores principales:	Sonia N. Acharya, Ruth V. Nichols, Lauren E. Rylaarsdam, Brendan L. O’Connell, Theodore P. Braun, Andrew C. Adey
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-07-01
Colección:	Genome Biology
Materias:	Single-cell Epigenetics DNA methylation
Acceso en línea:	https://doi.org/10.1186/s13059-024-03306-7
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