An In-Silico Identification of Potential Flavonoids against Kidney Fibrosis Targeting TGFβR-1

Fibrosis is a hallmark of progressive kidney diseases. The overexpression of profibrotic cytokine, namely transforming growth factor β (TGF-β) due to excessive inflammation and tissue damage, induces kidney fibrosis. The inhibition of TGF-β signaling is markedly limited in experimental disease model...

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Autors principals:	MD. Hasanur Rahman, Partha Biswas, Dipta Dey, Md. Abdul Hannan, Md. Sahabuddin, Yusha Araf, Youngjoo Kwon, Talha Bin Emran, Md. Sarafat Ali, Md Jamal Uddin
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-11-01
Col·lecció:	Life
Matèries:	kidney fibrosis chronic kidney disease TGFβR-1 flavonoids pharmacokinetics molecular docking
Accés en línia:	https://www.mdpi.com/2075-1729/12/11/1764
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