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Untargeted metabolomics reveals gut microbiota metabolite alterations and their correlation with serum biomarkers in gastric cancer patients from high-altitude regions

Abstract Objective This study aimed to characterize gut microbiota-derived faecal metabolites and evaluate their associations with serum biochemical indices and tumor markers in gastric cancer patients residing in high-altitude regions, using untargeted metabolomics. Methods Stool samples from 30 ne...

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Principais autores: Linghong Zhu, Zhaoxin Jin, Yanqing Ma, Xiao Feng, Caihong Ci, Yunsong Zhou, Qiaoling Gu, Yongmei Lan, Zilong Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2025-10-01
Serier:Discover Oncology
Fag:
High-altitude gastric cancer
Gut microbiota metabolites
Untargeted metabolomics
Serum biomarkers
Tumor markers
Metabolic profiling
Online adgang:https://doi.org/10.1007/s12672-025-03388-0
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