Toxicological impact of benzo[a]pyrene on esophageal cancer: an integrated analysis via network toxicology, machine learning, and molecular docking

BackgroundTo investigate the mechanisms underlying benzo[a]pyrene-induced esophageal cancer (EC), and to screen and identify the key targets and biomarkers associated with benzo[a]pyrene-related EC.MethodsPotential targets of benzo[a]pyrene (BaP) were predicted using PharmMapper, SwissTargetPredicti...

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Detalhes bibliográficos

Principais autores:	Xuyan Lan, Zuqiang Huang, Yukun Lin, Xiaoyu Sun, Binghan Guo, Genglin Li, Jintao Wang, Jinlan Lin, Lihuan Zhu, Tianxing Guo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-07-01
coleção:	Frontiers in Immunology
Assuntos:	benzo[a]pyrene esophageal cancer molecular docking network toxicology single-cell RNA sequencing
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1881352/full
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