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Beyond Allotypes: The Influence of Allelic Diversity in Antibody Constant Domains

Polymorphic diversity in antibody constant domains has long been defined by allotypic motifs that cross react with the sera of other individuals. Improvements in sequencing technologies have led to the discovery of a large number of new allelic sequences that underlie this diversity. Many of the poi...

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Autori principali: Annmaree K. Warrender, William Kelton
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020-08-01
Serie:Frontiers in Immunology
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Accesso online:https://www.frontiersin.org/article/10.3389/fimmu.2020.02016/full
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