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Unveiling the anti-inflammatory potential of olive leaf phenolic extracts in diabetes-related endothelial dysfunction

IntroductionDiabetes mellitus is a severe metabolic disorder strongly linked to vascular complications driven by endothelial dysfunction, chronic inflammation, and oxidative stress. Novel strategies to mitigate endothelial activation are urgently needed. In this context, phenolic compounds derived f...

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Principais autores: Ilaria Cappellacci, Nadia Di Pietrantonio, Davide Viola, Gloria Formoso, Małgorzata Elżbieta Zujko, Beatriz Martín-García, Ana M. Gomez-Caravaca, Vito Verardo, Assunta Pandolfi, Caterina Pipino
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-10-01
coleção:Frontiers in Endocrinology
Assuntos:
endothelial inflammation
olive leaf polyphenols
diabetes mellitus
NF-κB signaling pathway
VCAM-1 expression
monocyte adhesion
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fendo.2025.1671932/full
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