The tryptophan-kynurenine pathway in cardiovascular diseases: mechanistic insights and therapeutic opportunities

Cardiovascular diseases (CVDs) are the leading cause of death worldwide, making them crucial to further explore their mechanisms. Beyond traditional risk factors, disturbances in tryptophan metabolism, particularly the imbalance in the kynurenine pathway (KP) which accounts for over 95% of metabolic...

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Autores principales:	Wei Chen, Min Shui, Zhen Wei, Weiyan Gao, Xin Liu, Qian Lei
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2026-03-01
Colección:	Frontiers in Cardiovascular Medicine
Materias:	cardiovascular diseases kynurenine pathway metabolomics tryptophan metabolism treatment
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fcvm.2026.1726522/full
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