2-O, 3-O desulfated heparin mitigates murine chemotherapy- and radiation-induced thrombocytopenia

Abstract: Thrombocytopenia is a significant complication of chemotherapy and radiation therapy. Platelet factor 4 (PF4; CXCL4) is a negative paracrine of megakaryopoiesis. We have shown that PF4 levels are inversely related to steady-state platelet counts, and to the duration and severity of chemoth...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Elizabeth Tkaczynski, Abinaya Arulselvan, John Tkaczynski, Stephen Avery, Liqing Xiao, Beverly Torok-Storb, Kraig Abrams, Narayanam V. Rao, Gregory Johnson, Thomas P. Kennedy, Mortimer Poncz, Michele P. Lambert
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2018-04-01
Sarja:	Blood Advances
Linkit:	http://www.sciencedirect.com/science/article/pii/S2473952920310430
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