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Brain-Derived Neurotrophic Factor (BDNF) Preserves the Functional Integrity of Neural Networks in the β-Amyloidopathy Model in vitro

Alzheimer’s disease (AD) is a widespread chronic neurodegenerative pathology characterized by synaptic dysfunction, partial neuronal death, cognitive decline and memory impairments. The major hallmarks of AD are extracellular senile amyloid plaques formed by various types of amyloid proteins (Aβ) an...

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Principais autores: Elena V. Mitroshina, Roman S. Yarkov, Tatiana A. Mishchenko, Victoria G. Krut’, Maria S. Gavrish, Ekaterina A. Epifanova, Alexey A. Babaev, Maria V. Vedunova
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-07-01
Serier:Frontiers in Cell and Developmental Biology
Fag:
neural networks
Alzheimer’s disease
β-amyloidopathy
brain-derived neurotrophic factor
microelectrode arrays
calcium imaging
Online adgang:https://www.frontiersin.org/article/10.3389/fcell.2020.00582/full
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