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24S-Hydroxycholesterol Correlates With Tau and Is Increased in Cerebrospinal Fluid in Parkinson's Disease and Corticobasal Syndrome

24S-hydroxycholesterol (24OHC) and Tau are produced in neuronal cells and neurodegeneration leads to increased flux of both of them into cerebrospinal fluid (CSF). In the present study, CSF levels of 24OHC and 27S-hydroxycholesterol (27OHC) along with those of Tau, P-Thr181-Tau and Aβ42 were measure...

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Detalhes bibliográficos
Principais autores: Ingemar Björkhem, Kalicharan Patra, Adam L. Boxer, Per Svenningsson
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-09-01
coleção:Frontiers in Neurology
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fneur.2018.00756/full
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