Hypothermic machine perfusion prevents hyperacute graft loss in pig-to-primate kidney xenotransplantation after 5-hours of cold Ischemia

Abstract Background Xenotransplantation (XTx) is a promising strategy to address the organ shortage. Clinical application will likely require off-site procurement from designated pathogen-free (DPF) facilities, introducing unavoidable cold ischemic time (CIT). The impact of CIT and organ preservatio...

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Egile Nagusiak:	Yu Hisadome, Daniel L. Eisenson, WeiLi Chen, Alexander C. Schulick, Adam Luo, Michelle R. Santillan, Kelly Casella, Du Gu, Mitsuhiro Sekijima, Hisashi Sahara, Daniel Warren, Andrew Cameron, Hayato Iwase, Eugene Shenderov, Kazuhiko Yamada
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2025-04-01
Saila:	Communications Medicine
Sarrera elektronikoa:	https://doi.org/10.1038/s43856-025-00842-6
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