Ailanthone ameliorates pulmonary fibrosis by suppressing JUN-dependent MEOX1 activation

Pulmonary fibrosis poses a significant health threat with very limited therapeutic options available. In this study, we reported the enhanced expression of mesenchymal homobox 1 (MEOX1) in pulmonary fibrosis patients, especially in their fibroblasts and endothelial cells, and confirmed MEOX1 as a ce...

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Detalhes bibliográficos

Principais autores:	Lixin Zhao, Yuguang Zhu, Hua Tao, Xiying Chen, Feng Yin, Yingyi Zhang, Jianfeng Qin, Yongyin Huang, Bikun Cai, Yonghao Lin, Jiaxiang Wu, Yu Zhang, Lu Liang, Ao Shen, Xi-Yong Yu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-08-01
coleção:	Acta Pharmaceutica Sinica B
Assuntos:	Ailanthone MEOX1 Pulmonary fibrosis JUN TGF-β1 High-throughput screening
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211383524001424
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