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Clinical outcome of Brazilian patients with non-small cell lung cancer in early stage harboring rare mutations in epidermal growth factor receptor

The common epidermal growth factor receptor (EGFR) mutations, such as the L858R point mutation in exon 21 and the in-frame deletional mutation in exon 19, have been definitively associated with response to EGFR-tyrosine kinase inhibitors (EGFR-TKI). However, the clinical outcome and response to trea...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: J. Machado-Rugolo, C.M. Baldavira, T.G. Prieto, E.H.R. Olivieri, A.T. Fabro, C.A. Rainho, E.C. Castelli, P.E.M. Ribolla, A.M. Ab'Saber, T. Takagaki, M.A. Nagai, V.L. Capelozzi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Associação Brasileira de Divulgação Científica 2023-01-01
Schriftenreihe:Brazilian Journal of Medical and Biological Research
Schlagworte:
Lung cancer
Next generation sequencing
Rare EGFR mutation
Platinum-based chemotherapy
Erlotinib
Online-Zugang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2022000100687&tlng=en
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