Cofilin-actin rod formation in experimental stroke is attenuated by therapeutic hypothermia and overexpression of the inducible 70 kD inducible heat shock protein (Hsp70)

BACKGROUND AND PURPOSE: Cofilin-actin rods are covalently linked aggregates of cofilin-1 and actin. Under ischemic conditions, these rods have been observed in neuronal dendrites and axons and may contribute to the loss of these processes. Hypothermia (Hypo) and the 70 kD inducible heat shock protei...

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Prif Awduron:	Kota Kurisu, Jesung You, Zhen Zheng, Seok Joon Won, Raymond A Swanson, Midori A Yenari
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Wolters Kluwer Medknow Publications 2019-01-01
Cyfres:	Brain Circulation
Pynciau:	cofilin-actin rod heat shock protein 70 hypothermia neuroprotection stroke
Mynediad Ar-lein:	http://www.braincirculation.org/article.asp?issn=2394-8108;year=2019;volume=5;issue=4;spage=225;epage=233;aulast=Kurisu
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