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Case Report: Abnormalities of sperm motility and morphology in a patient with Leber hereditary optic neuropathy: Improvement after idebenone therapy

CaseWe report the sperm characteristics of a male patient who developed, when he was 18 years old, a Leber hereditary optic neuropathy, a hereditary optic neuropathy due to mtDNA mutation as well as variants in the nuclear DNA. At the age of 30 years-old, he complained of infertility lasting for 2 y...

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Principais autores: Christophe Orssaud, Virginie Barraud Lange, Jean Philippe Wolf, Nathalie LeFoll, Jean Claude Soufir
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-01-01
coleção:Frontiers in Neurology
Assuntos:
Leber hereditary optic neuropathy
spermatogenesis
sperm motility
idebenone
mtDNA mutation
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fneur.2022.946559/full
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