Safety and pathological impact of resection after high-dose PBT for locally advanced pancreatic cancer

Abstract Background A multidisciplinary approach is essential for treating lethal pancreatic cancer. Proton beam therapy (PBT), with its potential for dose escalation, shows promising effect for the local tumor, but the safety of subsequent resection and its pathological impact remain uncertain. Met...

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Detalhes bibliográficos

Principais autores:	Osamu Shimomura, Haruko Numajiri, Shinji Hashimoto, Yoshihiro Miyazaki, Manami Doi, Hiromitsu Nakahashi, Kazuhiro Takahashi, Yuichi Hiroshima, Naoyuki Hasegawa, Masato Endo, Yusuke Niisato, Yuya Hagiwara, Yoshiyuki Yamamoto, Takeshi Yamada, Noriaki Sakamoto, Daisuke Matsubara, Bryan J. Mathis, Kiichiro Tsuchiya, Hideyuki Sakurai, Tatsuya Oda
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-10-01
coleção:	World Journal of Surgical Oncology
Assuntos:	Locally advanced pancreatic cancer Proton beam therapy Multidisciplinary Hyperthermia Pathological findings Complications
Acesso em linha:	https://doi.org/10.1186/s12957-025-03992-y
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