Quinoline-thiosemicarbazone-1,2,3-triazole-acetamide derivatives as new potent α-glucosidase inhibitors

Abstract In this work, a novel series of quinoline-thiosemicarbazone-1,2,3-triazole-aceamide derivatives 10a-n as new potent α-glucosidase inhibitors was designed, synthesized, and evaluated. All the synthesized derivatives 10a-n were more potent than acarbose (positive control). Representatively, (...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Aynaz Khademian, Mohammad Halimi, Reza Azarbad, Amir Hossein Alaedini, Milad Noori, Navid Dastyafteh, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Maryam Mohammadi-Khanaposhtani, Mohammad Mahdavi
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Portfolio 2024-12-01
Sarja:	Scientific Reports
Aiheet:	Quinoline Thiosemicarbazone 1,2,3-Triazole α-Glucosidase inhibitors
Linkit:	https://doi.org/10.1038/s41598-024-81668-5
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