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Glucosamine induces apoptosis of cholangiocarcinoma cells by suppressing high-mannose type N-glycosylation and EGFR/STAT3 signaling

Aim This study aimed to investigate the effects of glucosamine, a glucose analogue mainly transported via glucose transporter (GLUT) 2, on the progression of cholangiocarcinoma (CCA) cells.Methods Differential expressions of GLUTs in CCA and normal bile ducts were analyzed using a public transcripto...

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Autori principali: Orawan Waenphimai, Cheerapinya Taebprakhon, Chatchai Phoomak, Chen Chu, Atit Silsirivanit, Sopit Wongkham, Charupong Saengboonmee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis Group 2026-12-01
Serie:Future Science OA
Soggetti:
Cholangiocarcinoma
food supplement
glucosamine
intracellular signaling
N-glycosylation
Accesso online:https://www.tandfonline.com/doi/10.1080/20565623.2026.2641244
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