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Identifying patterns to uncover the importance of biological pathways on known drug repurposing scenarios

Abstract Background Drug repurposing plays a significant role in providing effective treatments for certain diseases faster and more cost-effectively. Successful repurposing cases are mostly supported by a classical paradigm that stems from de novo drug development. This paradigm is based on the “on...

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Principais autores: Belén Otero-Carrasco, Esther Ugarte Carro, Lucía Prieto-Santamaría, Marina Diaz Uzquiano, Juan Pedro Caraça-Valente Hernández, Alejandro Rodríguez-González
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-01-01
coleção:BMC Genomics
Assuntos:
Drug repurposing
Pathway-based
DISNET knowledge
Computational biology
Data-driven methodology
Acesso em linha:https://doi.org/10.1186/s12864-023-09913-1
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