Lapatinib, Nilotinib and Lomitapide Inhibit Haemozoin Formation in Malaria Parasites

With the continued loss of antimalarials to resistance, drug repositioning may have a role in maximising efficiency and accelerating the discovery of new antimalarial drugs. Bayesian statistics was previously used as a tool to virtually screen USFDA approved drugs for predicted β-haematin (synthetic...

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Autores principales:	Ana Carolina C. de Sousa, Keletso Maepa, Jill M. Combrinck, Timothy J. Egan
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2020-03-01
Colección:	Molecules
Materias:	β-haematin haemozoin virtual screening docking drug repurposing <i>Plasmodium</i>
Acceso en línea:	https://www.mdpi.com/1420-3049/25/7/1571
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