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Valproic acid, a histone deacetylase inhibitor, enhances radiosensitivity in breast cancer cell line

Purpose: Valproic acid (VPA) is used mainly for the treatment of epilepsy and other seizure disorders, however, it is known to be one of histone deacetylase (HDAC) inhibitors. HDACIs have represented roles in radiation-sensitizing of cancer cells. This study is aimed to study to evaluate the radiose...

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Principais autores: Ahmad Yarmohamadi, Jahanbakhsh Asadi, Roghaye Gharaei, Mostafa Mir, Alireza Khoshbin Khoshnazar
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2018-01-01
coleção:Journal of Radiation and Cancer Research
Assuntos:
Acesso em linha:http://www.journalrcr.org/article.asp?issn=0973-0168;year=2018;volume=9;issue=2;spage=86;epage=92;aulast=Yarmohamadi
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