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Dysregulation of MicroRNA-181a-5p Targets TNFAIP3 to Promote MIF-CXCR4 Signaling and Immune Inflammatory Remodeling in Chronic Myeloid Leukemia [version 3; peer review: 1 approved, 2 approved with reservations]

Background The non-coding RNAs, particularly microRNA-181a-5p target the expression of tumor necrosis factor alpha-induced protein 3 (TNFAIP3) a key negative regulator of NF-κB signaling and affect the levels of macrophage migration inhibitory factor (MIF) and chemokine receptor type 4 (CXCR4) in ch...

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Principais autores: Noha Mohammed Saleh, Rawaa AlChalabi, Yasir Issa, Shahad Nassurat
Format: Artigo
Sprog:Inglês
Udgivet: F1000 Research Ltd 2026-03-01
Serier:F1000Research
Fag:
Chronic myeloid leukemia
CXCR4
Immune biomarkers
Inflammation
MIF
miR-181a
eng
Online adgang:https://f1000research.com/articles/14-1460/v3
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