Activation status of astrocytes drives the MS/NMOSD therapeutic paradox: Insights from IFNAR1 signaling

Summary: Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune inflammatory disease of the central nervous system (CNS) that, despite overlapping phenotypic features with multiple sclerosis (MS), manifests with more severe clinical outcomes. The defining pathogenic driver of NMOSD is t...

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Главные авторы:	Luhang Dai, Guo Cheng, Tingting Cui, Sitong He, Ran Wang, Jingqi Kang, Pei Li, Xin Zhang, Xiaoli Ding, Xiaochang Xue, Luting Yang, Yaling Zhang, Yaping Yan
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2026-02-01
Серии:	Cell Reports
Предметы:	CP: neuroscience CP: cell biology
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2211124725016857
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