Increased Orexin by High Concentration of Sevoflurane Enhances the Suprahyoid Muscle Activity Involves in Gasping‐Like Respiration of Mice

ABSTRACT Gasping respiration enhances survival chances during cardiac arrest by activating the suprahyoid muscles (SHMs), which are crucial for airway dilation. We previously reported that the high concentration of sevoflurane (6.5%: 2.0 minimum alveolar concentration, MAC) leads to gasping‐like res...

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Detalhes bibliográficos

Principais autores:	Yoko Irukayama‐Tomobe, Jun‐Dal Kim, Hisayo Jin, Saki Taiji, Tsuyoshi Nemoto, Dai Horiuchi, Yunosuke Ogata, Tomoya Hamamura, Tomoko Misawa, Takashi Kanbayashi, Takashi Nishino, Shiroh Isono, Takuji Suzuki, Yoshitoshi Kasuya, Koichiro Tatsumi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2026-01-01
coleção:	FASEB BioAdvances
Assuntos:	gasping respiration hypothalamic transcriptome orexin sevoflurane suprahyoid muscle
Acesso em linha:	https://doi.org/10.1096/fba.2025-00272
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