An interaction network of inner centriole proteins organised by POC1A-POC1B heterodimer crosslinks ensures centriolar integrity

Abstract Centriole integrity, vital for cilia formation and chromosome segregation, is crucial for human health. The inner scaffold within the centriole lumen composed of the proteins POC1B, POC5 and FAM161A is key to this integrity. Here, we provide an understanding of the function of inner scaffol...

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Autors principals:	Cornelia Sala, Martin Würtz, Enrico Salvatore Atorino, Annett Neuner, Patrick Partscht, Thomas Hoffmann, Sebastian Eustermann, Elmar Schiebel
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-11-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-024-54247-5
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