KBTBD8/RRP15 as a potential novel therapeutic target associates with lenvatinib-inhibited progression in hepatocellular carcinoma both in vitro and in vivo

Introduction: We have previously demonstrated that RRP15 (Ribosomal RNA Processing 15 Homolog) was significantly elevated in hepatocellular carcinoma (HCC) and correlated directly with poor prognosis. RRP15 suppression curtails HCC progression through induction of cellular senescence and apoptosis....

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Hauptverfasser:	Saili Zhao, Xuran Wang, Rui Wu, Fenglan Wang, Xiaoxuan Tang, Junhui Chen, Runqiu Jiang, Wei Kang, Guifang Xu, Lei Wang, Zhangding Wang, Xiaoping Zou, Bin Zhang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2025-10-01
Schriftenreihe:	Journal of Advanced Research
Schlagworte:	RRP15 Hepatocellular carcinoma KBTBD8 Metastasis Proteasomal degradation
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2090123224005940
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