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Case Report: Myeloid neoplasms with the t(3;12)(q26.2;p13.1)/MECOM-ETV6 translocation: report of two new cases and review of the literature

The MECOM (MDS1 and EVI1 complex locus) gene, located at 3q26.2, encodes an oncogenic transcription factor implicated in multiple signaling pathways. Rearrangements involving MECOM/3q26.2, including inversions, translocations, insertions and cryptic chromosomal changes, are observed in myeloid neopl...

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Wedi'i Gadw mewn:
Prif Awduron: Soumya Mikkilineni, Juan Pablo Pineda-Reyes, Lindsay Wilde, Andres Ferber, Zi-Xuan Wang, Stephen Peiper, Guldeep Uppal, Jerald Gong, Jinglan Liu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2025-04-01
Cyfres:Frontiers in Oncology
Pynciau:
t(3;12)
MECOM
ETV6
cytogenetics
myeloid
neoplasms
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fonc.2025.1526044/full
Tagiau: Ychwanegu Tag
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