Consequences of a high incidence of microsatellite instability and BRAF‐mutated tumors: A population‐based cohort of metastatic colorectal cancer patients

Abstract Background Immunotherapy for patients with microsatellite‐instable (MSI‐H) tumors or BRAF‐inhibitors combination treatment for BRAF‐mutated (mutBRAF) tumors in metastatic colorectal cancer (mCRC) is promising, but the frequency of these molecular changes in trial patients are low. Unselecte...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Kristine Ø. Aasebø, Anca Dragomir, Magnus Sundström, Artur Mezheyeuski, Per‐Henrik Edqvist, Geir Egil Eide, Fredrik Ponten, Per Pfeiffer, Bengt Glimelius, Halfdan Sorbye
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2019-07-01
Schriftenreihe:	Cancer Medicine
Schlagworte:	colorectal neoplasm microsatellite instability proto‐oncogene proteins B‐raf prognosis neoplasm metastasis
Online-Zugang:	https://doi.org/10.1002/cam4.2205
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!