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Co-Crystal Structures of Furosemide:Urea and Carbamazepine:Indomethacin Determined from Powder X-Ray Diffraction Data

Co-crystallization is a promising approach to improving both the solubility and the dissolution rate of active pharmaceutical ingredients. Crystal structure determination from powder diffraction data plays an important role in determining co-crystal structures, especially those generated by mechanoc...

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Principais autores: Okba Al Rahal, Mridul Majumder, Mark J. Spillman, Jacco van de Streek, Kenneth Shankland
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-01-01
Serier:Crystals
Fag:
co-crystal
powder diffraction
global optimization
dft
pharmaceuticals
rietveld refinement
Online adgang:https://www.mdpi.com/2073-4352/10/1/42
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