Novel Optineurin Frameshift Insertion in a Family With Frontotemporal Dementia and Parkinsonism Without Amyotrophic Lateral Sclerosis

Frontotemporal Dementia (FTD) is a common cause of Young Onset Dementia and has diverse clinical manifestations involving behavior, executive function, language and motor function, including parkinsonism. Up to 50% of FTD patients report a positive family history, supporting a strong genetic basis,...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Jacqueline Dominguez, Jeryl Tan Yu, Yi Jayne Tan, Arlene Ng, Ma Fe De Guzman, Boots Natividad, Ma Luisa Daroy, Jemellee Cano, Justine Yu, Michelle M. Lian, Li Zeng, Weng Khong Lim, Jia Nee Foo, Adeline S. L. Ng
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-05-01
Schriftenreihe:	Frontiers in Neurology
Schlagworte:	familial FTD novel mutation parkinsonism amyotrophic lateral scelerosis optineurin (OPTN)
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fneur.2021.645913/full
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