HNF4A and HNF1A exhibit tissue specific target gene regulation in pancreatic beta cells and hepatocytes
Abstract HNF4A and HNF1A encode transcription factors that are important for the development and function of the pancreas and liver. Mutations in both genes have been directly linked to Maturity Onset Diabetes of the Young (MODY) and type 2 diabetes (T2D) risk. To better define the pleiotropic gene...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Portfolio
2024-06-01
|
| Sarja: | Nature Communications |
| Linkit: | https://doi.org/10.1038/s41467-024-48647-w |
| Tagit: |
Ei tageja, Lisää ensimmäinen tagi!
|