Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease

Chronic graft-versus-host disease (cGVHD) is mediated by specific CD4 and B cells, but the relative contribution of extrafollicular and germinal centre (GC) T-B interaction is unclear. Here the authors show that the extrafollicular expansion of a specific CD4 T subset is sufficient for inducing cGVH...

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Auteurs principaux:	Ruishu Deng, Christian Hurtz, Qingxiao Song, Chanyu Yue, Gang Xiao, Hua Yu, Xiwei Wu, Markus Muschen, Stephen Forman, Paul J. Martin, Defu Zeng
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2017-10-01
Collection:	Nature Communications
Accès en ligne:	https://doi.org/10.1038/s41467-017-00880-2
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