An oncostatin M receptor and chloride intracellular channel 1 crosstalk drives key oncogenic pathways in glioblastoma

Abstract Oncostatin M receptor (OSMR) plays diverse roles in several human malignancies, including brain, breast, and pancreatic cancer. In glioblastoma (GB), OSMR orchestrates a feedforward signaling mechanism with the truncated active mutant of epidermal growth factor receptor (EGFR), the EGFRvIII...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Amir Hossein Mansourabadi, Dianbo Qu, Francesca Cianci, Jamie Snider, Kamaldeep Randhawa, Laura Raco, Max Kotlyar, Mohammad Al Ayach, Guido Rey, Shridhar Sanghvi, Mark Abovsky, Harpreet Singh, H. Artee Luchman, Dylan Burger, Janusz Rak, Vahab D. Soleimani, Igor Jurisica, Igor Stagljar, Michele Mazzanti, Arezu Jahani-Asl
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Publishing Group 2026-05-01
Цуврал:	Signal Transduction and Targeted Therapy
Онлайн хандалт:	https://doi.org/10.1038/s41392-026-02723-3
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!