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Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli

Abstract Background Children with autism spectrum disorder (ASD) have urinary metabolites suggesting impairments in several pathways, including oxidative stress, inflammation, mitochondrial dysfunction, and gut microbiome alterations. Sulforaphane, a supplement with indirect antioxidant effects that...

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Principais autores: Stephen Bent, Brittany Lawton, Tracy Warren, Felicia Widjaja, Katherine Dang, Jed W. Fahey, Brian Cornblatt, Jason M. Kinchen, Kevin Delucchi, Robert L. Hendren
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-05-01
coleção:Molecular Autism
Assuntos:
Autism
Metabolomics
Antioxidant
Biomarker
Acesso em linha:http://link.springer.com/article/10.1186/s13229-018-0218-4
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