GRWD1 enhances HSV-1 replication by facilitating nuclear egress
ABSTRACT Herpes simplex virus 1 (HSV-1) depends on host factors for its replication. Here, we identify glutamate-rich WD40 repeat-containing 1 (GRWD1) as a novel pro-viral host factor that facilitates HSV-1 nuclear egress. GRWD1 knockdown trapped nucleocapsids in the nucleus and suppressed viral rep...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology
2026-06-01
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| Seria: | Microbiology Spectrum |
| Hasła przedmiotowe: | |
| Dostęp online: | https://journals.asm.org/doi/10.1128/spectrum.01608-25 |
| Etykiety: |
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