Har-P, a short P-element variant, weaponizes P-transposase to severely impair Drosophila development

Without transposon-silencing Piwi-interacting RNAs (piRNAs), transposition causes an ovarian atrophy syndrome in Drosophila called gonadal dysgenesis (GD). Harwich (Har) strains with P-elements cause severe GD in F1 daughters when Har fathers mate with mothers lacking P-element-piRNAs (i.e. ISO1 str...

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Autores principales:	Satyam P Srivastav, Reazur Rahman, Qicheng Ma, Jasmine Pierre, Saptaparni Bandyopadhyay, Nelson C Lau
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	eLife Sciences Publications Ltd 2019-12-01
Colección:	eLife
Materias:	P-element piRNA gonadal dysgenesis transposon silencing
Acceso en línea:	https://elifesciences.org/articles/49948
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