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The Interferon-signature of Sjögren’s Syndrome: How Unique Biomarkers Can Identify Underlying Inflammatory and Immunopathological Mechanisms of Specific Diseases

Innate immune responses direct the nature and specificity of downstream adaptive responses in autoimmune diseases. One of the strongest markers of innate immunity is the up-regulated expression of interferon (IFN) and IFN-responsive/stimulated genes (IRGs/ISGs). While multiple IRGs are induced durin...

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Bibliografiske detaljer
Principais autores: Cuong eNguyen, Ammon B. Peck
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013-07-01
Serier:Frontiers in Immunology
Fag:
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00142/full
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