Thrombomodulin favors leukocyte microvesicle fibrinolytic activity, reduces NETosis and prevents septic shock-induced coagulopathy in rats

Abstract Background Septic shock-induced disseminated intravascular coagulation is responsible for increased occurrence of multiple organ dysfunction and mortality. Immunothrombosis-induced coagulopathy may contribute to hypercoagulability. We aimed at determining whether recombinant human thrombomo...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Julie Helms, Raphaël Clere-Jehl, Elsa Bianchini, Pierrick Le Borgne, Mélanie Burban, Fatiha Zobairi, Jean-Luc Diehl, Lelia Grunebaum, Florence Toti, Ferhat Meziani, Delphine Borgel
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2017-12-01
Sarja:	Annals of Intensive Care
Aiheet:	DIC Immunothrombosis Microvesicles NETosis Septic shock
Linkit:	http://link.springer.com/article/10.1186/s13613-017-0340-z
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