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Heme Oxygenase-1 Inhibition Modulates Autophagy and Augments Arsenic Trioxide Cytotoxicity in Pancreatic Cancer Cells

Pancreatic ductal adenocarcinoma (PDAC) is the most prevalent form, accounting for more than 90% of all pancreatic malignancies. In a previous study, we found that hypoxia and chemotherapy induced expression of Heme Oxygenase-1 (HO-1) in PDAC cells and tissues. Arsenic trioxide (ATO) is the first-li...

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Autores principales: Iman M. Ahmad, Alicia J. Dafferner, Ramia J. Salloom, Maher Y. Abdalla
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2023-09-01
Colección:Biomedicines
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Acceso en línea:https://www.mdpi.com/2227-9059/11/9/2580
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