Diacylglycerol kinase (DGKA) regulates the effect of the epilepsy and bipolar disorder treatment valproic acid in Dictyostelium discoideum

Valproic acid (VPA) provides a common treatment for both epilepsy and bipolar disorder; however, common cellular mechanisms relating to both disorders have yet to be proposed. Here, we explore the possibility of a diacylglycerol kinase (DGK) playing a role in regulating the effect of VPA relating to...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Elizabeth Kelly, Devdutt Sharma, Christopher J. Wilkinson, Robin S. B. Williams
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	The Company of Biologists 2018-09-01
Schriftenreihe:	Disease Models & Mechanisms
Schlagworte:	Diacyclglycerol Diacylglycerol kinase Dictyostelium discoideum Epilepsy Lithium Valproic acid
Online-Zugang:	http://dmm.biologists.org/content/11/9/dmm035600
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