Nucleosome wrapping energy in CpG islands and the role of epigenetic base modifications
The majority of vertebrate promoters have a distinct DNA composition, known as a CpG island. Cytosine methylation in promoter CpG islands is associated with a substantial reduction of transcription initiation. We hypothesise that both atypical sequence composition and epigenetic base modifications m...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications Ltd
2025-12-01
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| Colecção: | eLife |
| Assuntos: | |
| Acesso em linha: | https://elifesciences.org/articles/98468 |
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