Structural rationale to understand the effect of disease-associated mutations on Myotubularin
Myotubularin or MTM1 is a lipid phosphatase that regulates vesicular trafficking in the cell. The MTM1 gene is mutated in a severe form of muscular disease, X-linked myotubular myopathy or XLMTM, affecting 1 in 50,000 newborn males worldwide. There have been several studies on the disease pathology...
Furkejuvvon:
| Váldodahkkit: | , , , , |
|---|---|
| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Elsevier
2023-01-01
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| Ráidu: | Current Research in Structural Biology |
| Fáttát: | |
| Liŋkkat: | http://www.sciencedirect.com/science/article/pii/S2665928X23000065 |
| Fáddágilkorat: |
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